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BMCBI
2010
13 years 5 months ago
2010
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
BMCBI
2010
13 years 5 months ago
2010
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
BIOINFORMATICS
2011
13 years 5 months ago
2011
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
BMCBI
2011
13 years 5 months ago
2011
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
BMCBI
2011
13 years 5 months ago
2011
Background: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measure...