Switching between two modes of operation is a common property of biological systems. In continuous-time differential equation models, this is often realised by bistability, i.e. th...
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
Sorting is a memory intensive operation whose performance is greatly affected by the amount of memory available as work space. When the input size is unknown or available memory s...
A genetic algorithm scheme with a stochastic genotype/phenotype relation is proposed. The mechanisms responsible for this intermediate level of uncertainty, are inspired by the bio...
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...