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» Rich probabilistic models for gene expression
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BMCBI
2011
13 years 2 months ago
Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets
Background: The combination of genotypic and genome-wide expression data arising from segregating populations offers an unprecedented opportunity to model and dissect complex phen...
Kyle C. Chipman, Ambuj K. Singh
RECOMB
2002
Springer
14 years 8 months ago
Probabilistic hierarchical clustering for biological data
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...
Eran Segal, Daphne Koller
RECOMB
2004
Springer
14 years 8 months ago
Learning Regulatory Network Models that Represent Regulator States and Roles
Abstract. We present an approach to inferring probabilistic models of generegulatory networks that is intended to provide a more mechanistic representation of transcriptional regul...
Keith Noto, Mark Craven
ICANN
2007
Springer
14 years 1 months ago
Structure Learning with Nonparametric Decomposable Models
Abstract. We present a novel approach to structure learning for graphical models. By using nonparametric estimates to model clique densities in decomposable models, both discrete a...
Anton Schwaighofer, Mathäus Dejori, Volker Tr...
RECOMB
2007
Springer
14 years 8 months ago
A Bayesian Model That Links Microarray mRNA Measurements to Mass Spectrometry Protein Measurements
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Anitha Kannan, Andrew Emili, Brendan J. Frey