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BMCBI
2010
99views more  BMCBI 2010»
13 years 6 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BIRTHDAY
2005
Springer
14 years 7 days ago
Still
Keywords Name of the disease and synonyms Definition/Diagnostic criteria Juvenile form Comments on the differential diagnosis Incidence Clinical description Method of biological d...
Alice ter Meulen
SIGMOD
2010
ACM
324views Database» more  SIGMOD 2010»
13 years 11 months ago
Similarity search and locality sensitive hashing using ternary content addressable memories
Similarity search methods are widely used as kernels in various data mining and machine learning applications including those in computational biology, web search/clustering. Near...
Rajendra Shinde, Ashish Goel, Pankaj Gupta, Debojy...
BMCBI
2008
110views more  BMCBI 2008»
13 years 6 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...
BMCBI
2007
104views more  BMCBI 2007»
13 years 6 months ago
Predicting active site residue annotations in the Pfam database
Background: Approximately 5% of Pfam families are enzymatic, but only a small fraction of the sequences within these families (<0.5%) have had the residues responsible for cata...
Jaina Mistry, Alex Bateman, Robert D. Finn