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» SAT-based protein design
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BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
VLSID
2010
IEEE
155views VLSI» more  VLSID 2010»
13 years 5 months ago
Synchronized Generation of Directed Tests Using Satisfiability Solving
Directed test generation is important for the functional verification of complex system-on-chip designs. SAT based bounded model checking is promising for counterexample generatio...
Xiaoke Qin, Mingsong Chen, Prabhat Mishra
CSB
2003
IEEE
14 years 27 days ago
A New Similarity Measure among Protein Sequences
Protein sequence analysis is an important tool to decode the logic of life. One of the most important similarity measures in this area is the edit distance between amino acids of ...
Kuen-Pin Wu, Hsin-Nan Lin, Ting-Yi Sung, Wen-Lian ...
BMCBI
2007
175views more  BMCBI 2007»
13 years 7 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
BMCBI
2008
178views more  BMCBI 2008»
13 years 7 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...