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» SCOP: a Structural Classification of Proteins database
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BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2008
103views more  BMCBI 2008»
13 years 7 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
DWARF - a data warehouse system for analyzing protein families
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
BMCBI
2007
156views more  BMCBI 2007»
13 years 7 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee
NAR
2007
127views more  NAR 2007»
13 years 7 months ago
The Universal Protein Resource (UniProt)
The Universal Protein Resource (UniProt) provides the scientific community with a single, centralized, authoritative resource for protein sequences and functional information. For...