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» SIMAGE: simulation of DNA-microarray gene expression data
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ALIFE
1998
13 years 7 months ago
The Perfect C. elegans Project: An Initial Report
The soil nematode Caenorhabditis Elegans (C. elegans) is the most investigated of all multi-cellular organisms. Since the proposal to use it as a model organism, a series of resea...
Hiroaki Kitano, Shugo Hamahashi, Sean Luke
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
New resampling method for evaluating stability of clusters
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
Irina Gana Dresen, Tanja Boes, Johannes Hüsin...
BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Testing for treatment effects on gene ontology
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
Taewon Lee, Varsha G. Desai, Cruz Velasco, Robert ...
BMCBI
2007
104views more  BMCBI 2007»
13 years 7 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
ICAI
2007
13 years 9 months ago
Mining and Dynamic Simulation of Sub-Networks from Large Biomolecular Networks
Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As biomolecular...
Xiaohua Hu, Fang-Xiang Wu, Michael K. Ng, Bahrad A...