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BMCBI
2006
152views more  BMCBI 2006»
13 years 9 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
BMCBI
2008
200views more  BMCBI 2008»
13 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
ICTAI
2007
IEEE
14 years 3 months ago
Accurate Classification of SAGE Data Based on Frequent Patterns of Gene Expression
In this paper we present a method for classifying accurately SAGE (Serial Analysis of Gene Expression) data. The high dimensionality of the data, namely the large number of featur...
George Tzanis, Ioannis P. Vlahavas
BMCBI
2010
100views more  BMCBI 2010»
13 years 9 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2007
79views more  BMCBI 2007»
13 years 9 months ago
Orthology prediction at scalable resolution by phylogenetic tree analysis
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
René T. J. M. van der Heijden, Berend Snel,...