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BMCBI
2010
126views more  BMCBI 2010»
13 years 6 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
BMCBI
2002
188views more  BMCBI 2002»
13 years 8 months ago
The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
Background: The biomedical community is developing new methods of data analysis to more efficiently process the massive data sets produced by microarray experiments. Systematic an...
David M. Mutch, Alvin Berger, Robert Mansourian, A...
BMCBI
2011
13 years 3 months ago
The dChip survival analysis module for microarray data
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
Samir B. Amin, Parantu K. Shah, Aimin Yan, Sophia ...
BMCBI
2007
126views more  BMCBI 2007»
13 years 9 months ago
Including probe-level uncertainty in model-based gene expression clustering
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
Xuejun Liu, Kevin K. Lin, Bogi Andersen, Magnus Ra...
BMCBI
2006
85views more  BMCBI 2006»
13 years 9 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...