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BMCBI
2004
123views more  BMCBI 2004»
13 years 7 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
Luis Sánchez-Pulido, Ana María Rojas...
BMCBI
2002
76views more  BMCBI 2002»
13 years 7 months ago
The SGS3 protein involved in PTGS finds a family
Background: Post transcriptional gene silencing (PTGS) is a recently discovered phenomenon that is an area of intense research interest. Components of the PTGS machinery are being...
Alex Bateman
BMCBI
2002
126views more  BMCBI 2002»
13 years 7 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
COMPUTER
2002
89views more  COMPUTER 2002»
13 years 7 months ago
A Pattern for Softcoded Values
rs use models or abstractions that hide low-level implementation details. Various kinds of representations such as data models, state-transition models, and dataflow models can hel...
Michael R. Blaha, Cheryl Smith