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» Searching on the Secondary Structure of Protein Sequences
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FPL
2004
Springer
109views Hardware» more  FPL 2004»
14 years 23 days ago
Hardware Accelerated Novel Protein Identification
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BIOSYSTEMS
2007
104views more  BIOSYSTEMS 2007»
13 years 7 months ago
New structural variation in evolutionary searches of RNA neutral networks
RNA secondary structure is an important computational model to understand how genetic variation maps into phenotypic (structural) variation. Evolutionary innovation in RNA structu...
Sumedha, Olivier C. Martin, Andreas Wagner
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
BMCBI
2007
143views more  BMCBI 2007»
13 years 7 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos