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» Searching on the Secondary Structure of Protein Sequences
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BMCBI
2007
94views more  BMCBI 2007»
13 years 7 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
13 years 11 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
CIKM
2008
Springer
13 years 9 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang
BMCBI
2010
127views more  BMCBI 2010»
13 years 7 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
MitoRes: a resource of nuclear-encoded mitochondrial genes and their products in Metazoa
Background: Mitochondria are sub-cellular organelles that have a central role in energy production and in other metabolic pathways of all eukaryotic respiring cells. In the last f...
Domenico Catalano, Flavio Licciulli, Antonio Turi,...