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    BMCBI
    2007
    111views more  BMCBI 2007»
    MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
    13 years 9 months ago
    MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
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    Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
    Mamoru Kato, Tatsuhiko Tsunoda
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    BMCBI
    2007
    102views more  BMCBI 2007»
    Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
    13 years 9 months ago
    Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
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    Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
    Luis A. Diago, Persy Morell, Longendri Aguilera, E...
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    BMCBI
    2007
    141views more  BMCBI 2007»
    Artificial neural network models for prediction of intestinal permeability of oligopeptides
    13 years 9 months ago
    Artificial neural network models for prediction of intestinal permeability of oligopeptides
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    Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
    Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...
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    BMCBI
    2007
    154views more  BMCBI 2007»
    h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
    13 years 9 months ago
    h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
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    Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
    Yvonne E. Pittelkow, Susan R. Wilson
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    BMCBI
    2007
    77views more  BMCBI 2007»
    The reactive metabolite target protein database (TPDB) - a web-accessible resource
    13 years 9 months ago
    The reactive metabolite target protein database (TPDB) - a web-accessible resource
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    Background: The toxic effects of many simple organic compounds stem from their biotransformation to chemically reactive metabolites which bind covalently to cellular proteins. To ...
    Robert P. Hanzlik, Yakov M. Koen, Bhargav Theertha...
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