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» Semantics of Biological Regulatory Networks
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BMCBI
2007
167views more  BMCBI 2007»
13 years 7 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
CGF
2008
142views more  CGF 2008»
13 years 7 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
14 years 1 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
CIBCB
2009
IEEE
13 years 5 months ago
An automatic gene ontology software tool for bicluster and cluster comparisons
We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster...
Fadhl M. Al-Akwaa, Yasser M. Kadah
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
14 years 1 months ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke