Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
Lawrence J. K. Wee, Tin Wee Tan, Shoba Ranganathan
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Clustering with partial supervision finds its application in situations where data is neither entirely nor accurately labeled. This paper discusses a semisupervised clustering algo...
Annotating genes and their products with Gene Ontology codes is an important area of research. One approach for doing this is to use the information available about these genes in...