Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
Background: The most popular methods for significance analysis on microarray data are well suited to find genes differentially expressed across predefined categories. However, ide...
Lars Halvor Gidskehaug, Endre Anderssen, Arnar Fla...
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...