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» Sequence Alignment as a Database Technology Challenge
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BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2007
175views more  BMCBI 2007»
13 years 7 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...
RECOMB
2004
Springer
14 years 7 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
ICDE
2005
IEEE
157views Database» more  ICDE 2005»
14 years 8 months ago
MoDB: Database System for Synthesizing Human Motion
Enacting and capturing real motion for all potential scenarios is terribly expensive; hence, there is a great demand to synthetically generate realistic human motion. However, it ...
Timothy Edmunds, S. Muthukrishnan, Subarna Sadhukh...
BMCBI
2007
265views more  BMCBI 2007»
13 years 7 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...