60 search results - page 6 / 12 » Sequence kernels for predicting protein essentiality |
ISMB
2000
13 years 8 months ago
2000
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
BMCBI
2010
13 years 7 months ago
2010
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
NAR
2008
13 years 7 months ago
2008
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
BMCBI
2008
13 years 7 months ago
2008
Background: The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us...
BMCBI
2007
13 years 7 months ago
2007
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...