151 search results - page 18 / 31 » Sequence variation in ligand binding sites in proteins |
BMCBI
2006
13 years 7 months ago
2006
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...
BMCBI
2007
13 years 7 months ago
2007
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
ALMOB
2006
13 years 7 months ago
2006
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
BIOINFORMATICS
2011
12 years 11 months ago
2011
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
ICASSP
2007
IEEE
14 years 1 months ago
2007
IEEE
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...