151 search results - page 19 / 31 » Sequence variation in ligand binding sites in proteins |
PSB
2004
13 years 8 months ago
2004
This paper introduces the first integrated algorithm designed to discover novel motifs in heterogeneous sequence data, which is comprised of coregulated genes from a single genome...
BMCBI
2008
13 years 7 months ago
2008
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
ECCB
2002
IEEE
14 years 10 days ago
2002
IEEE
The dynamics of ligand-protein interactions are necessary to understand for the design of novel therapeutic agents. In this paper, we establish the use of Stochastic Roadmap Simul...
BMCBI
2005
13 years 7 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
BMCBI
2006
13 years 7 months ago
2006
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...