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» Sequence variation in ligand binding sites in proteins
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BMCBI
2007
151views more  BMCBI 2007»
13 years 7 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
BMCBI
2007
179views more  BMCBI 2007»
13 years 7 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BMCBI
2002
109views more  BMCBI 2002»
13 years 7 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...