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» Sequence variation in ligand binding sites in proteins
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BMCBI
2008
121views more  BMCBI 2008»
13 years 8 months ago
BioSAVE: Display of scored annotation within a sequence context
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
Richard F. Pollock, Boris Adryan
BMCBI
2006
134views more  BMCBI 2006»
13 years 8 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2007
112views more  BMCBI 2007»
13 years 8 months ago
PFAAT version 2.0: A tool for editing, annotating, and analyzing multiple sequence alignments
Background: By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely used to ...
Daniel R. Caffrey, Paul H. Dana, Vidhya Mathur, Ma...
BICOB
2009
Springer
14 years 1 months ago
Computational Prediction of Genes Translationally Regulated by Cytoplasmic Polyadenylation Elements
Cytoplasmic post-transcriptional modification of mRNA transcripts in the form of polyadenylated (poly(A)) tails plays a key role in their translational control. The timing and degr...
Eric C. Rouchka, Xiangping Wang, James H. Graham, ...
ACMSE
2007
ACM
14 years 12 days ago
Finding association rules of cis-regulatory elements involved in alternative splicing
Alternative splicing (AS) is a major mechanism to generate protein diversity. A single gene might generate hundreds or even thousands of different proteins. Recently, powerful lar...
Jihye Kim, Sihui Zhao, Steffen Heber