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» Sequence variation in ligand binding sites in proteins
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RECOMB
2006
Springer
14 years 7 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
WABI
2001
Springer
13 years 11 months ago
A Chemical-Distance-Based Test for Positive Darwinian Selection
There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting p...
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Sham...
NAR
2011
248views Computer Vision» more  NAR 2011»
12 years 10 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
13 years 11 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee
ISWC
2006
IEEE
14 years 1 months ago
Discovering Characteristic Actions from On-Body Sensor Data
We present an approach to activity discovery, the unsupervised identification and modeling of human actions embedded in a larger sensor stream. Activity discovery can be seen as ...
David Minnen, Thad Starner, Irfan A. Essa, Charles...