Homology identification is the first step for many genomic studies. Current methods, based on sequence comparison, can result in a substantial number of mis-assignments due to the ...
BLASTP is the most popular tool to perform comparative sequence analysis of protein sequences. An exponential increase in the size of protein sequence databases in recent years, h...
Arpith C. Jacob, Joseph M. Lancaster, Jeremy Buhle...
We introduce new distance measures for the construction and analysis of phylogenies, focusing on thioredoxin-fold proteins. Our distance measures for tree construction are based o...
Chang Wang, Stephen D. Scott, Qingping Tao, Dmitri...
Prediction of protein secondary structure (alpha-helix, beta-sheet, coil) from primary sequence of amino acids is a very challenging task, and the problem has been approached from...
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...