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» Shotgun Protein Sequencing
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ALMOB
2006
138views more  ALMOB 2006»
13 years 10 months ago
An enhanced RNA alignment benchmark for sequence alignment programs
Background: The performance of alignment programs is traditionally tested on sets of protein sequences, of which a reference alignment is known. Conclusions drawn from such protei...
Andreas Wilm, Indra Mainz, Gerhard Steger
RECOMB
2009
Springer
14 years 10 months ago
Simultaneous Alignment and Folding of Protein Sequences
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
Bonnie Berger, Charles W. O'Donnell, Jér&oc...
ISMB
2000
13 years 11 months ago
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste
RECOMB
2002
Springer
14 years 10 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
BMCBI
2007
144views more  BMCBI 2007»
13 years 10 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...