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APBC
2004
13 years 10 months ago
Mega Weaver: A Simple Iterative Approach for BAC Consensus Assembly
Hierarchical genome assembly can be divided into three distinct stages: sequencing and assembling shotgun reads for each of a series of selected BAC clones; assembling the resulti...
Daolong Wang, Mario Lauria, Bo Yuan, Fred A. Wrigh...
BIOCOMP
2006
13 years 10 months ago
Finishing Repetitive Regions Automatically with Dupfinisher
Currently, the genome sequencing community is producing shotgun sequence data at a very high rate, but genome finishing is not keeping pace, even with the help from several automa...
Cliff Han, Patrick Chain
BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
Tracembler - software for in-silico chromosome walking in unassembled genomes
Background: Whole genome shotgun sequencing produces increasingly higher coverage of a genome with random sequence reads. Progressive whole genome assembly and eventual finishing ...
Qunfeng Dong, Matthew D. Wilkerson, Volker Brendel
BMCBI
2010
91views more  BMCBI 2010»
13 years 8 months ago
Coverage statistics for sequence census methods
We study the shape of coverage functions resulting from the sequencing of random genome fragments, and show that they can be described by Galton-Watson trees. This extends standar...
Steven N. Evans, Valerie Hower, Lior Pachter
JACM
2002
94views more  JACM 2002»
13 years 8 months ago
The greedy path-merging algorithm for contig scaffolding
Given a collection of contigs and mate-pairs. The Contig Scaffolding Problem is to order and orientate the given contigs in a manner that is consistent with as many mate-pairs as p...
Daniel H. Huson, Knut Reinert, Eugene W. Myers