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CSB
2003
IEEE
111views Bioinformatics» more  CSB 2003»
14 years 4 months ago
A Contradiction-Based Framework for Testing Gene Regulation Hypotheses
We have developed a mathematical framework for representing and testing hypotheses about gene, protein, and signaling molecule interactions. It takes a hierarchical, contradiction...
Steve Racunas, Nigam Shah, Nina V. Fedoroff
BMCBI
2006
107views more  BMCBI 2006»
13 years 11 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
GECCO
2005
Springer
186views Optimization» more  GECCO 2005»
14 years 4 months ago
Subproblem optimization by gene correlation with singular value decomposition
Several ways of using singular value decomposition (SVD), a linear algebra technique typically used for information retrieval, to decompose problems into subproblems are investiga...
Jacob G. Martin
BMCBI
2007
126views more  BMCBI 2007»
13 years 11 months ago
Including probe-level uncertainty in model-based gene expression clustering
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
Xuejun Liu, Kevin K. Lin, Bogi Andersen, Magnus Ra...
BMCBI
2010
132views more  BMCBI 2010»
13 years 11 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong