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BMCBI
2008
193views more  BMCBI 2008»
13 years 7 months ago
Missing value imputation for microarray gene expression data using histone acetylation information
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Qian Xiang, Xianhua Dai, Yangyang Deng, Caisheng H...
BMCBI
2007
134views more  BMCBI 2007»
13 years 7 months ago
Benchmarking natural-language parsers for biological applications using dependency graphs
Background: Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because di...
Andrew B. Clegg, Adrian J. Shepherd
BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
137views more  BMCBI 2007»
13 years 7 months ago
Bayesian refinement of protein functional site matching
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
Kanti V. Mardia, Vysaul B. Nyirongo, Peter J. Gree...
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