103 search results - page 14 / 21 » Simulating the Hallmarks of Cancer |
BMCBI
2010
13 years 8 months ago
2010
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
BMCBI
2008
13 years 8 months ago
2008
Background: In cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: r...
BMCBI
2007
13 years 8 months ago
2007
Background: This paper presents a unified framework for finding differentially expressed genes (DEGs) from the microarray data. The proposed framework has three interrelated modul...
BMCBI
2008
13 years 8 months ago
2008
Background: Mixture models of mutagenetic trees are evolutionary models that capture several pathways of ordered accumulation of genetic events observed in different subsets of pa...
BMCBI
2008
13 years 8 months ago
2008
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...