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» Simulation sampling with live-points
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APLAS
2007
ACM
14 years 1 months ago
Scalable Simulation of Cellular Signaling Networks
Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
Vincent Danos, Jérôme Feret, Walter F...
BCS
2008
13 years 10 months ago
Beatbox - A Computer Simulation Environment for Computational Biology of the Heart
Despite over a century's study, the trigger mechanisms of cardiac arrhythmias are poorly understood. Even modern experimental methods do not provide sufficient temporal and s...
Ross McFarlane, Irina V. Biktasheva
BMCBI
2008
146views more  BMCBI 2008»
13 years 9 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
BMCBI
2011
13 years 4 months ago
Statistical learning techniques applied to epidemiology: a simulated case-control comparison study with logistic regression
Background: When investigating covariate interactions and group associations with standard regression analyses, the relationship between the response variable and exposure may be ...
John J. Heine, Walker H. Land Jr., Kathleen M. Ega...
BMCBI
2007
172views more  BMCBI 2007»
13 years 9 months ago
Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks
Background: Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly su...
Fulvia Ferrazzi, Paola Sebastiani, Marco Ramoni, R...