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BMCBI
2010
100views more  BMCBI 2010»
13 years 10 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2007
103views more  BMCBI 2007»
13 years 10 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2008
100views more  BMCBI 2008»
13 years 10 months ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
CN
2008
80views more  CN 2008»
13 years 10 months ago
Practical large-scale latency estimation
We present the implementation of a large-scale latency estimation system based on GNP and incorporated into the Google content delivery network. Our implementation does not rely o...
Michal Szymaniak, David L. Presotto, Guillaume Pie...
CORR
2010
Springer
149views Education» more  CORR 2010»
13 years 10 months ago
Group Testing with Probabilistic Tests: Theory, Design and Application
Identification of defective members of large populations has been widely studied in the statistics community under the name of group testing. It involves grouping subsets of items...
Mahdi Cheraghchi, Ali Hormati, Amin Karbasi, Marti...