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» Smoothing Gene Expression Using Biological Networks
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AUTOMATICA
2008
78views more  AUTOMATICA 2008»
13 years 9 months ago
A mathematical framework for the control of piecewise-affine models of gene networks
This article introduces results on the control of gene networks, in the context of piecewise-affine models. We propose an extension of this well-documented class of models, where ...
Etienne Farcot, Jean-Luc Gouzé
BMCBI
2006
165views more  BMCBI 2006»
13 years 9 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2008
98views more  BMCBI 2008»
13 years 9 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2007
116views more  BMCBI 2007»
13 years 9 months ago
Ranked Adjusted Rand: integrating distance and partition information in a measure of clustering agreement
Background: Biological information is commonly used to cluster or classify entities of interest such as genes, conditions, species or samples. However, different sources of data c...
Francisco R. Pinto, João A. Carriço,...
JCP
2008
121views more  JCP 2008»
13 years 9 months ago
Towards Design Space Exploration for Biological Systems
For both embedded systems and biological cell systems, design is a feature that defines their identity. The assembly of different components in designs of both systems can vary wid...
Simon Polstra, Tessa E. Pronk, Andy D. Pimentel, T...