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» Smoothing Gene Expression Using Biological Networks
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IJBRA
2008
66views more  IJBRA 2008»
13 years 7 months ago
Integer programming-based approach to allocation of reporter genes for cell array analysis
Abstract Observing behaviors of protein pathways and genetic networks under various environments in living cells is essential for unraveling disease and developing drugs. For that ...
Morihiro Hayashida, Fuyan Sun, Sachiyo Aburatani, ...
RECOMB
2003
Springer
14 years 8 months ago
Whole-genome comparative annotation and regulatory motif discovery in multiple yeast species
In [13] we reported the genome sequences of S. paradoxus, S. mikatae and S. bayanus and compared these three yeast species to their close relative, S. cerevisiae. Genome-wide comp...
Manolis Kamvysselis, Nick Patterson, Bruce Birren,...
CIBB
2008
13 years 9 months ago
Curating a Large-Scale Regulatory Network by Evaluating Its Consistency with Expression Datasets
Abstract. The analysis of large-scale regulatory models using data issued from genome-scale high-throughput experimental techniques is an actual challenge in the systems biology fi...
Carito Guziolowski, Jeremy Gruel, Ovidiu Radulescu...
BMCBI
2007
159views more  BMCBI 2007»
13 years 7 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
GLVLSI
2003
IEEE
175views VLSI» more  GLVLSI 2003»
14 years 1 months ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...