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» Smoothing Gene Expression Using Biological Networks
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RECOMB
2010
Springer
13 years 9 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
NAR
2011
224views Computer Vision» more  NAR 2011»
12 years 10 months ago
KaPPA-View4: a metabolic pathway database for representation and analysis of correlation networks of gene co-expression and meta
Correlations of gene-to-gene co-expression and metabolite-to-metabolite co-accumulation calculated from large amounts of transcriptome and metabolome data are useful for uncoverin...
Nozomu Sakurai, Takeshi Ara, Yoshiyuki Ogata, Ryos...
CCE
2005
13 years 7 months ago
Large-scale inference of the transcriptional regulation of Bacillus subtilis
This paper addresses the inference of the transcriptional regulatory network of Bacillus subtilis. Two inference approaches, a linear, additive model and a non-linear power-law mo...
Anshuman Gupta, Jeffrey D. Varner, Costas D. Maran...
RECOMB
2005
Springer
14 years 8 months ago
Reconstruction of Reticulate Networks from Gene Trees
Abstract. One of the simplest evolutionary models has molecular sequences evolving from a common ancestor down a bifurcating phylogenetic tree, experiencing point-mutations along t...
Daniel H. Huson, Tobias H. Klöpper, Pete J. L...
BMCBI
2010
201views more  BMCBI 2010»
13 years 5 months ago
IntelliGO: a new vector-based semantic similarity measure including annotation origin
Background: The Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular component aspects of gene annotation. I...
Sidahmed Benabderrahmane, Malika Smaïl-Tabbon...