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» Smoothing Gene Expression Using Biological Networks
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RECOMB
2004
Springer
14 years 8 months ago
Reconstructing reticulate evolution in species: theory and practice
We present new methods for reconstructing reticulate evolution of species due to events such as horizontal transfer or hybrid speciation; both methods are based upon extensions of...
Luay Nakhleh, Tandy Warnow, C. Randal Linder
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A robust measure of correlation between two genes on a microarray
Background: The underlying goal of microarray experiments is to identify gene expression patterns across different experimental conditions. Genes that are contained in a particula...
Johanna S. Hardin, Aya Mitani, Leanne Hicks, Brian...
BMCBI
2007
215views more  BMCBI 2007»
13 years 7 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
BMCBI
2010
99views more  BMCBI 2010»
13 years 7 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen