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BMCBI
2007
105views more  BMCBI 2007»
13 years 9 months ago
Extended analysis of benchmark datasets for Agilent two-color microarrays
Background: As part of its broad and ambitious mission, the MicroArray Quality Control (MAQC) project reported the results of experiments using External RNA Controls (ERCs) on fiv...
Kathleen F. Kerr
BMCBI
2007
169views more  BMCBI 2007»
13 years 9 months ago
The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats
Background: In Archeae and Bacteria, the repeated elements called CRISPRs for "clustered regularly interspaced short palindromic repeats" are believed to participate in ...
Ibtissem Grissa, Gilles Vergnaud, Christine Pource...
BMCBI
2007
77views more  BMCBI 2007»
13 years 9 months ago
The reactive metabolite target protein database (TPDB) - a web-accessible resource
Background: The toxic effects of many simple organic compounds stem from their biotransformation to chemically reactive metabolites which bind covalently to cellular proteins. To ...
Robert P. Hanzlik, Yakov M. Koen, Bhargav Theertha...
BMCBI
2007
120views more  BMCBI 2007»
13 years 9 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
BMCBI
2007
106views more  BMCBI 2007»
13 years 9 months ago
Simultaneous identification of long similar substrings in large sets of sequences
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
Jürgen Kleffe, Friedrich Möller, Burghar...
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