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» Somatic evolution of cancer
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CBMS
2004
IEEE
13 years 11 months ago
Image Segmentation of Uterine Cervix Images for Indexing in PACS
The National Cancer Institute has collected a large database of digitized 35mm slides of the uterine cervix, the idea being to build a system enabling to study the evolution of le...
Shiri Gordon, Gali Zimmerman, Hayit Greenspan
EVOW
2006
Springer
13 years 11 months ago
Hierarchical Clustering, Languages and Cancer
In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustnes...
Pritha Mahata, Wagner Costa, Carlos Cotta, Pablo M...
RECOMB
2009
Springer
14 years 2 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...
BMCBI
2005
91views more  BMCBI 2005»
13 years 7 months ago
COPASAAR - A database for proteomic analysis of single amino acid repeats
Background: Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and med...
Daniel P. Depledge, Andrew R. Dalby
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya