Motivation: Extracting functional information from protein–protein interactions (PPI) poses significant challenges arising from the noisy, incomplete, generic and static nature...
There are very few instances in which positive Darwinian selection has been convincingly demonstrated at the molecular level. In this study, we present a novel test for detecting p...
Tal Pupko, Roded Sharan, Masami Hasegawa, Ron Sham...
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...