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» Statistical analysis of domains in interacting protein pairs
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VIS
2005
IEEE
204views Visualization» more  VIS 2005»
14 years 10 months ago
Differential Protein Expression Analysis via Liquid-Chromatography/Mass-Spectrometry Data Visualization
Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...
Lars Linsen, Julia Löcherbach, Matthias Berth...
JCB
2007
144views more  JCB 2007»
13 years 9 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2008
176views more  BMCBI 2008»
13 years 9 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
BMCBI
2007
133views more  BMCBI 2007»
13 years 9 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
LREC
2008
134views Education» more  LREC 2008»
13 years 10 months ago
Dependency-Based Relation Mining for Biomedical Literature
We describe techniques for the automatic detection of relationships among domain entities (e.g. genes, proteins, diseases) mentioned in the biomedical literature. Our approach is ...
Fabio Rinaldi, Gerold Schneider, Kaarel Kaljurand,...