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» Statistical analysis of domains in interacting protein pairs
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BMCBI
2006
180views more  BMCBI 2006»
13 years 9 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2010
132views more  BMCBI 2010»
13 years 9 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
BMCBI
2006
181views more  BMCBI 2006»
13 years 9 months ago
Array2BIO: from microarray expression data to functional annotation of co-regulated genes
Background: There are several isolated tools for partial analysis of microarray expression data. To provide an integrative, easy-to-use and automated toolkit for the analysis of A...
Gabriela G. Loots, Patrick S. G. Chain, Shalini Ma...
VIS
2009
IEEE
238views Visualization» more  VIS 2009»
14 years 10 months ago
An Interactive Visualization Tool for Multi-channel Confocal Microscopy Data in Neurobiology Research
Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channe...
Yong Wan, Hideo Otsuna, Chi-Bin Chien, Charles ...
BMCBI
2007
122views more  BMCBI 2007»
13 years 9 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...