311 search results - page 54 / 63 » Statistical significance in biological sequence analysis |
BMCBI
2004
13 years 7 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
IADIS
2008
13 years 9 months ago
2008
One approach to reduce the complexity of the task in the analysis of large scale genome-wide expression is to group the genes showing similar expression patterns into what are cal...
BMCBI
2010
13 years 7 months ago
2010
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
BMCBI
2007
13 years 7 months ago
2007
Background: The study of microRNAs (miRNAs) is attracting great considerations. Recent studies revealed that miRNAs play as important regulators of gene expression and some even a...
BMCBI
2010
13 years 7 months ago
2010
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...