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» Strategies in Rigid-Variable Methods
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BMCBI
2010
96views more  BMCBI 2010»
13 years 8 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2010
113views more  BMCBI 2010»
13 years 8 months ago
Class prediction for high-dimensional class-imbalanced data
Background: The goal of class prediction studies is to develop rules to accurately predict the class membership of new samples. The rules are derived using the values of the varia...
Rok Blagus, Lara Lusa
BMCBI
2010
224views more  BMCBI 2010»
13 years 8 months ago
An adaptive optimal ensemble classifier via bagging and rank aggregation with applications to high dimensional data
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...
Susmita Datta, Vasyl Pihur, Somnath Datta
BMCBI
2007
182views more  BMCBI 2007»
13 years 8 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...
BMCBI
2007
133views more  BMCBI 2007»
13 years 8 months ago
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Oscar Conchillo-Solé, Natalia S. de Groot, ...