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» Structural Protein Interactions: From Months to Minutes
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BMCBI
2006
180views more  BMCBI 2006»
13 years 8 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
PRIB
2009
Springer
100views Bioinformatics» more  PRIB 2009»
14 years 3 months ago
Evidence-Based Clustering of Reads and Taxonomic Analysis of Metagenomic Data
Abstract. The rapidly emerging field of metagenomics seeks to examine the genomic content of communities of organisms to understand their roles and interactions in an ecosystem. I...
Gianluigi Folino, Fabio Gori, Mike S. M. Jetten, E...
ALGORITHMICA
2008
115views more  ALGORITHMICA 2008»
13 years 8 months ago
Algorithm Engineering for Color-Coding with Applications to Signaling Pathway Detection
Color-coding is a technique to design fixed-parameter algorithms for several NP-complete subgraph isomorphism problems. Somewhat surprisingly, not much work has so far been spent ...
Falk Hüffner, Sebastian Wernicke, Thomas Zich...
NAR
2010
94views more  NAR 2010»
13 years 3 months ago
Saccharomyces Genome Database provides mutant phenotype data
The Saccharomyces Genome Database (SGD; http:// www.yeastgenome.org) is a scientific database for the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which i...
Stacia R. Engel, Rama Balakrishnan, Gail Binkley, ...
BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone