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BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Statistical significance of cis-regulatory modules
Background: It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding si...
Dustin E. Schones, Andrew D. Smith, Michael Q. Zha...
BMCBI
2007
86views more  BMCBI 2007»
13 years 7 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
BMCBI
2008
242views more  BMCBI 2008»
13 years 7 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2010
87views more  BMCBI 2010»
13 years 7 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
FragViz: visualization of fragmented networks
Background: Researchers in systems biology use network visualization to summarize the results of their analysis. Such networks often include unconnected components, which popular ...
Miha Stajdohar, Minca Mramor, Blaz Zupan, Janez De...
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