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BMCBI
2011
12 years 10 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
KDD
2007
ACM
209views Data Mining» more  KDD 2007»
14 years 7 months ago
Temporal causal modeling with graphical granger methods
The need for mining causality, beyond mere statistical correlations, for real world problems has been recognized widely. Many of these applications naturally involve temporal data...
Andrew Arnold, Yan Liu, Naoki Abe
BIBE
2007
IEEE
128views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
QOMA2: Optimizing the alignment of many sequences
Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
Xu Zhang, Tamer Kahveci
ASMTA
2008
Springer
167views Mathematics» more  ASMTA 2008»
13 years 8 months ago
Perfect Simulation of Stochastic Automata Networks
The solution of continuous and discrete-time Markovian models is still challenging mainly when we model large complex systems, for example, to obtain performance indexes of paralle...
Paulo Fernandes, Jean-Marc Vincent, Thais Webber
SODA
2008
ACM
110views Algorithms» more  SODA 2008»
13 years 8 months ago
Why simple hash functions work: exploiting the entropy in a data stream
Hashing is fundamental to many algorithms and data structures widely used in practice. For theoretical analysis of hashing, there have been two main approaches. First, one can ass...
Michael Mitzenmacher, Salil P. Vadhan