Abstract. Over the last decade several prediction methods have been developed for determining structural and functional properties of individual protein residues using sequence and...
Huzefa Rangwala, Christopher Kauffman, George Kary...
We show that a classifier based on Gaussian mixture models (GMM) can be trained discriminatively to improve accuracy. We describe a training procedure based on the extended Baum-W...
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
A computationally efficient approach to local learning with kernel methods is presented. The Fast Local Kernel Support Vector Machine (FaLK-SVM) trains a set of local SVMs on redu...
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...