Abstract—Higher organisms are able to respond to continuously changing external conditions by transducing cellular signals into specific regulatory programs, which control gene ...
This paper presents GMLE 1 , a generic and distributed framework for maximum likelihood evaluation. GMLE is currently being applied to astroinformatics for determining the shape o...
Travis J. Desell, Nathan Cole, Malik Magdon-Ismail...
Background: For effective exposition of biological information, especially with regard to analysis of large-scale data types, researchers need immediate access to multiple categor...
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...