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» Systematic calibration of a cell signaling network model
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RECOMB
2006
Springer
14 years 7 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
ISCAS
2007
IEEE
179views Hardware» more  ISCAS 2007»
14 years 1 months ago
Analysis for Signal and Power Integrity Using the Multilayered Finite Difference Method
— We present a method for fast analysis of signal and power integrity based on a recently developed multilayered finite difference method (M-FDM). In order to accurately model m...
Ege Engin, Krishna Bharath, Madhavan Swaminathan
JCB
2006
125views more  JCB 2006»
13 years 7 months ago
Hypothesis Generation in Signaling Networks
Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulati...
Derek A. Ruths, Luay Nakhleh, M. Sriram Iyengar, S...
BMCBI
2006
205views more  BMCBI 2006»
13 years 7 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
CEC
2009
IEEE
13 years 11 months ago
A model for intrinsic artificial development featuring structural feedback and emergent growth
Abstract--A model for intrinsic artificial development is introduced in this paper. The proposed model features a novel mechanism where growth emerges, rather than being triggered ...
Martin Trefzer, Tüze Kuyucu, Julian Francis M...