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BMCBI
2007
86views more  BMCBI 2007»
13 years 8 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...
NIPS
2004
13 years 10 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
BMCBI
2007
136views more  BMCBI 2007»
13 years 8 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
CSB
2005
IEEE
135views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Relating transcription factors, modules of genes and cultivation conditions in Saccharomyces cerevisiae
Usually, the functionality of a module of co-expressed genes is derived from enrichment within the module of a particular gene annotation category. The systematic setup of the che...
Theo A. Knijnenburg, Marcel J. T. Reinders, J. M. ...
BMCBI
2010
118views more  BMCBI 2010»
13 years 8 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...