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BMCBI
2007
109views more  BMCBI 2007»
13 years 8 months ago
TABASCO: A single molecule, base-pair resolved gene expression simulator
Background: Experimental studies of gene expression have identified some of the individual molecular components and elementary reactions that comprise and control cellular behavio...
Sriram Kosuri, Jason R. Kelly, Drew Endy
BMCBI
2007
108views more  BMCBI 2007»
13 years 8 months ago
Publishing perishing? Towards tomorrow's information architecture
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
Michael R. Seringhaus, Mark B. Gerstein
BMCBI
2008
111views more  BMCBI 2008»
13 years 8 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express
Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Chih-Hung Jen, Tsun-Po Yang, Chien-Yi Tung, Shu-Ha...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
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